Blogs
Series: Let’s build a stack – Fat Loss
š§¬Ā Fat Loss Peptide Stacks Overview
šøĀ BRONZE STACK ā Metabolic Priming & FFA Oxidation
Goal:Ā Initiate fat loss through appetite suppression, enhanced fatty acid transport and oxidation, with basic mitochondrial support.
Components:
- Retatrutide
Appetite suppression, insulin sensitivity, basal metabolic rate increase - L-CarnitineĀ (Oral or IM, 1ā2g/day)
Fatty acid transport into mitochondria for oxidation - SLU-PP-332Ā (or MOTS-c)
Increases oxidative metabolism and fatty acid oxidation (SLU-PP-332)
Boosts mitochondrial respiration and metabolic flexibility (MOTS-c)
Why Each Compound is Included:
- Retatrutide: Enhances fat loss by controlling appetite and improving insulin sensitivity.
- L-Carnitine: Essential for fatty acid transport to mitochondria for oxidation and energy production.
- SLU-PP-332Ā (or MOTS-c): Supports mitochondrial oxidation and endurance, enhancing fat burning and metabolic capacity.
šĀ SILVER STACK ā Fat Oxidation, GH Axis Activation & Mitochondrial Biogenesis
Goal:Ā Aggressive fat loss with GH support and improved mitochondrial function, preserving lean muscle mass.
Components:
- Retatrutide
Appetite suppression, insulin sensitivity, basal metabolic rate increase - CJC-1295 + IpamorelinĀ (5x/week SC)
GH secretion support for fat loss and muscle preservation - AOD-9604
Selective fat loss without impacting IGF-1 levels - L-CarnitineĀ (Injectable, 2g/day)
Fatty acid transport to mitochondria for oxidation - MOTS-cĀ (2ā3x/week SC)
Boosts mitochondrial respiration, fatty acid oxidation, and metabolic flexibility
Why Each Compound is Included:
- Retatrutide: Drives fat loss through appetite control and energy expenditure.
- CJC-1295 + Ipamorelin: StimulatesĀ GH productionĀ to enhance fat loss, preserve lean muscle, and optimize recovery.
- AOD-9604: TargetsĀ visceral fatĀ for fat loss without affecting muscle mass.
- L-Carnitine: Enhances fatty acid oxidation by improving fatty acid transport into mitochondria.
- MOTS-c: Aids mitochondrial biogenesis and fatty acid oxidation, improving overall metabolic efficiency.
š¶Ā GOLD STACK ā Elite Recomposition & Maximal Metabolic Efficiency
Goal:Ā Full-spectrum fat loss, lean muscle preservation, and optimized mitochondrial function with GH activation.
Components:
- Retatrutide
Appetite suppression, insulin sensitivity, basal metabolic rate increase - Tesamorelin + CJC-1295
GHRH analog + GH secretagogue for fat loss and lean mass preservation - AOD-9604
Targeted fat loss without IGF-1 interference - L-CarnitineĀ (Injectable, 2ā3g/day)
Fatty acid transport to mitochondria for oxidation - MOTS-c
Enhances mitochondrial function, metabolic flexibility, and fat oxidation - 5-Amino-1MQ
Boosts NAD+ and mitochondrial biogenesis for fat burning - CoQ10 (Ubiquinol, 100ā200mg/day)
Supports ATP production and mitochondrial efficiency
Why Each Compound is Included:
- Retatrutide: Continues to suppress appetite and enhance metabolic rate for fat loss.
- Tesamorelin + CJC-1295:Ā Stimulate GH productionĀ for fat loss and lean muscle preservation.
- AOD-9604: Specifically targets fat burning without affecting IGF-1 levels, ensuring lean mass retention.
- L-Carnitine: Essential for optimal fat oxidation, improving mitochondrial function and fat transport.
- MOTS-c: Supports mitochondrial function, increasing metabolic efficiency and fat oxidation during a caloric deficit.
- 5-Amino-1MQ: EnhancesĀ NAD+Ā levels, drivingĀ mitochondrial biogenesisĀ and improving fat burning.
- CoQ10: SupportsĀ ATP productionĀ in mitochondria, providing cellular energy for increased performance and fat loss.
š§¬Ā Stack Comparison Table
| Tier | Lipolysis | FFA Transport | Oxidation | Mitochondrial Biogenesis | GH Support | Specialty Agents |
|---|---|---|---|---|---|---|
| Bronze | ā | ā (L-Carnitine) | ā ā (SLU) | āŖļø (via PPARĪ“) | ā | ā (SLU-PP-332) |
| Silver | ā ā | ā ā | ā ā | ā (MOTS-c) | ā (CJC/Ipam) | ā (MOTS-c) |
| Gold | ā ā ā | ā ā ā | ā ā ā | ā ā ā (5-A1MQ, MOTS-c) | ā ā ā (Tesamorelin + CJC) | ā ā ā (MOTS-c, CoQ10) |
Key Points of Each Stack:
- Bronze: Entry-level for fat loss, with a focus onĀ fatty acid transportĀ and basic mitochondrial support. Ideal for beginners or those with less aggressive goals.
- Silver: Intermediate fat loss stack that introducesĀ GH support,Ā mitochondrial biogenesis, andĀ increased metabolic efficiency. Ideal for more advanced fat loss and muscle preservation.
- Gold: Advanced stack forĀ elite recomposition, combiningĀ GH stimulation,Ā mitochondrial optimization, andĀ maximized fat burning. Tailored for those looking to achieve peak body composition with sustained energy.